Tools for fragment based drug discovery

Head Start Projects


A different way to start

Head Start Projects offer a highly de-risked jumping off point for rapid structure based elaboration of novel, validated fragment hit matter.


All projects include:
  • Fully structural biology enabled by NMR, X-ray crystallography or both.
  • Optimized biophysical assays to interrogate specificity, affinity, stoichiometry and kinetics of ligand binding.
  • Novel, orthogonally validated fragment hits.

Head Start Projects are performed on a fee-for-service basis, with full transfer of all IP to the client.