Tools for fragment based drug discovery

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THE MARKET LEADING INNOVATOR OF BIOPHYSICAL TECHNIQUES TO SUPPORT MODERN DRUG DISCOVERY


In its 15 years of existence, ZoBio has integrated modern drug discovery technologies into an efficient
pipeline to support hit to lead programs on targets that no other CRO can address.

Starting with our proprietary Target Immobilized NMR Screening (TINS) technology, which has been used in over 80 projects, ZoBio delivers highly validated fragment ligands for a wide array of challenging targets. We are developing industry leading, innovative techniques to support FBDD, including novel NMR methods to rapidly elucidate the structure of target – ligand complexes.

Our exclusive NMR techniques and X-ray crystallography are used to steer hit-to-lead optimization and enable rapid progression of fragment hits into potent and ligand-efficient lead compounds. Combined with our in-house protein production, computational chemistry approaches, orthogonal validation methods and direct access to exclusive synthetic chemistry, ZoBio possesses all the tools to support Fragment Based Drug Discovery programs, from gene to lead.


Complete overview of our Drug Discovery Platform >