HEAD START PROJECTS
A different way to start
Head Start Projects offer a highly de-risked jumping off point for rapid structure based elaboration of novel, validated fragment hit matter.
All projects include:
- Fully structural biology enabled by NMR, X-ray crystallography or both.
- Optimized biophysical assays to interrogate specificity, affinity, stoichiometry and kinetics of ligand binding.
- Novel, orthogonally validated fragment hits.